Are there rules for thumb for deciding when you can dump a whole database and when you’d be better off dumping groups of tables? I have a database that has around 100 tables, some of them quite large, and right now the data directory is well over 100GB. My hunch is that I should divide and conquer, but I don’t have a clear sense of what counts as “too big” these days. Nor do I have a clear sense of whether the constraints have to do with overall size, the number of tables, or machine memory (my machine has 32GB of memory).
Is 10GB a good practical limit to keep in mind?
I'd say the rule-of-thumb is if you have to "divide-and-conquer" you should use non-pg_dump based backup solutions. Too big is usually measured in units of time, not memory.
Any ability to partition your backups into discrete chunks is going to be very specific to your personal setup. Restoring such a monster without constraint violations is something I'd be VERY worried about.