Any advices will help, see some information below:
Linux is CentOS release 6.4 (Final)
Do you have all the 103 database in one cluster ? I suspect a DISK IO and CPU spike. Do you see that ?
Ø Yes all 103 database are in one cluster
Its hard to say straight if there is a need for REINDEXING. Can you let us know the hardware specifications of the server.
We will need to understand if the server capacity is falling short for the load being received.
How many active connections you see at the database level ?
Ø Max connections is 200 because it was giving problems with 100 max connections
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